MLB Picks & Predictions for May 25, 2026 | SharpSide Model Divergences

Today, our model highlights two matchups where the market is significantly undervaluing offensive output. This presents opportunities for informed MLB bettors.

Washington Nationals @ Cleveland Guardians

The SharpSide model projects a 4.8-5.5 final score, a stark contrast to the market consensus of 3.6-4.5. This represents a total edge of +2.2 runs compared to market projections. With Zack Littell (5.83 ERA) on the mound for Washington and Tanner Bibee (3.75 ERA) for Cleveland, the market appears to be underestimating the scoring potential of both offenses in standard park and weather conditions. Model leans OVER.

Arizona Diamondbacks @ San Francisco Giants

Our analysis for the Diamondbacks and Giants shows a projected 4.4-5.2 score, differing from the 3.3-4.2 market consensus. This total edge of +2.1 runs suggests the market is underpricing run scoring in this game. Merrill Kelly (5.71 ERA) starts for Arizona against Landen Roupp (3.27 ERA) for San Francisco, and despite Roupp's lower ERA, the model sees more offense than the market implies. Park and weather conditions are not a factor. Model leans OVER.

How to read this

These are SharpSide model projections versus current market consensus. They indicate where our algorithms identify a significant discrepancy, not financial advice.